Enhanced Antibacterial Activity of Eugenol-Loaded mPEG-PCL Nanoparticles in Eliminating Resistant Bacteria from Wastewater

In this study, eugenol-loaded mPEG-PCL nanoparticles were used to improve the anti-bacterial properties of eugenol in an attempt eliminate resistant bacteria. The copolymer was prepared by ring-opening polymerization [Formula: see text]-caprolactone monomer vicinity a dry mPEG and tin (II) octoate catalyst. Polymeric through nanoprecipitation procedure. particle size zeta potential mPEG-PCL/eugenol found be text] nm mV, respectively. polymeric nanoparticle structure identified AFM, FT-IR, DSC techniques. To evaluate compare antibacterial efficiency with that free eugenol, turbidity assay association gram-positive gram-negative SEM images taken from bacteria before after exposure mPEG-PCL/eugenol. colony-forming unit per milliliter (CFU/mL) method performance on growth rate hospital wastewater. results showed demonstrated enormous effect connection wild strains at 40 text]M concentration 37 ∘ C. original wastewater, 0.125 25 C largest decrease total microbial count.